Neuropathy is a circulation and oxygenation crisis at the nerve level. SynergyO3 addresses its root drivers — vascular insufficiency, oxidative damage, nutrient depletion, and inflammation — through EBOO, regenerative biologics, and targeted IV therapy that support nerve repair from within.
Recognition is the first step. Dr. Volpp evaluates your complete clinical picture at your physician-led consultation.
Every patient begins with a consultation with Dr. Heather Volpp, MD. Your full clinical picture is reviewed before any protocol is designed.
SynergyO3 identifies upstream biological drivers — oxidative stress, toxin burden, immune dysregulation, pathogen load — rather than treating symptoms in isolation.
EBOO, HOCATT®, IV therapy, and regenerative biologics work as a system — addressing multiple physiological drivers simultaneously for compounding outcomes.
Peripheral neuropathy results from damage to the peripheral nerves — the vast network that transmits signals between the brain, spinal cord, and the rest of the body. It most commonly presents in the hands and feet with burning, numbness, tingling, and weakness.
The most common causes include diabetes, chemotherapy-induced neuropathy, autoimmune conditions, nutritional deficiencies (particularly B12 and folate), and chronic infections including Lyme disease. In many cases, the underlying driver is a combination of factors.
What all types share is a common physiology: damaged nerves that are under-oxygenated, inflamed, and starved of the nutrients required for repair. Addressing these upstream drivers — rather than just managing pain — is the foundation of SynergyO3's approach.
Every peripheral nerve is fed by small blood vessels called vasa nervorum. When circulation to these vessels is impaired, nerves are starved of oxygen and nutrients — accelerating damage and preventing repair.
Book Consultation →Gabapentin, pregabalin, and duloxetine reduce pain signals but do nothing to address the underlying nerve damage or restore function. Symptoms return when medications are reduced.
Most neuropathy treatment protocols do not address the vascular insufficiency driving nerve damage. Without improving blood flow to affected nerves, recovery is severely limited.
B12, B1, B6, folate, and alpha-lipoic acid are essential for nerve health. Deficiencies are common in neuropathy patients and rarely comprehensively assessed or corrected.
Extra-corporeal Blood Ozone and Oxygenation (EBOO) is a closed-circuit medical procedure that ozonates your blood outside the body — driving systemic physiological changes targeted at the specific mechanisms driving your condition.
EBOO improves red blood cell flexibility, oxygen delivery, and microvascular perfusion — directly addressing the vascular insufficiency that starves peripheral nerves of oxygen.
Ozone therapy modulates inflammatory pathways affecting nerve sheaths, reducing the neuroinflammatory burden that drives neuropathic pain and progressive damage.
Oxidative stress is a central driver of neuropathy progression. EBOO activates superoxide dismutase and glutathione — the body's primary neuroprotective antioxidant systems.
By reducing oxidative stress and improving oxygenation, EBOO creates the optimal cellular environment for myelin sheath repair and regeneration.
HOCATT®'s transdermal ozone, far-infrared heat, and carbonic acid work together to improve peripheral circulation, reduce musculoskeletal pain, and support detoxification. The thermal vasodilation effect specifically addresses the cold extremities and circulation deficits common in neuropathy — making it a highly targeted complement to EBOO's systemic vascular improvements.
Ask About HOCATT® →Ozone absorbed through skin delivers anti-inflammatory effects without the intensity of systemic EBOO.
Deep tissue heating supports detoxification, reduces musculoskeletal pain, and stimulates mitochondrial activity.
CO2 dissolved in steam causes potent vasodilation — improving peripheral circulation and oxygen delivery.
Completely non-invasive. Patients sit reclined inside the HOCATT® pod. No needles, no downtime.
In some cases, yes — particularly when caught early and when the underlying cause is addressable. In advanced cases, meaningful improvement in symptoms and functional quality of life is the primary goal.
Typically 6-10 sessions in the initial series. Neuropathy is a chronic condition and responds gradually. Many patients notice symptom improvement around session 3-4.
Yes — particularly for the cold extremities, pain, and circulatory component. Many neuropathy patients report significant symptomatic relief from HOCATT®.
Yes. Diabetic neuropathy is the most common type and responds to the EBOO + circulation + nutrient protocol. Blood sugar control must be optimized in parallel.
Yes. CIPN is one of the most common and undertreated sequelae of cancer treatment. The same oxygenation, antioxidant, and nutrient protocol applies.
Most patients report initial changes in symptom intensity within 3-4 EBOO sessions. Functional improvements typically emerge over 6-12 weeks of consistent protocol.
This depends on whether the underlying cause is resolved. If the driving factor is addressed, improvements can be sustained and progressive. Maintenance sessions may be recommended.
Insurance is not accepted. Superbills are available for HSA/FSA. Written pricing is provided before all services.
Before any treatment begins, Dr. Volpp reviews your complete health history, labs, and goals. Every protocol is physician-designed for your specific biology — not a template.
Book Your Consultation →(760) 450-4602 · info@synergyo3.com · Mon-Fri 9:00am-5:00pm
Insurance not accepted · HSA/FSA superbills available · Written quotes before all services