Medicine that treats the whole body
Physician-led integrative & regenerative medicine in Encinitas — supervised by Dr. Heather Volpp, MD.
We focus on the root contributors to chronic symptoms — inflammation, oxidative burden, and immune dysregulation — with protocols designed and supervised by a board-certified physician. Care that complements your existing treatment, never replaces it.
Board-certified internal medicine
Clinical practice
Supervised by Dr. Volpp, MD
Allergy & Immunology Fellowship · UCLA/VA · CA License A81147 · Physician-Owned & Operated
These statements have not been evaluated by the FDA. Our therapies are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.
— Physician-Led Integrative Medicine · Encinitas, CA
Medicine that treats the whole body
Physician-led integrative & regenerative medicine in Encinitas — supervised by Dr. Heather Volpp, MD.
We focus on the root contributors to chronic symptoms — inflammation, oxidative burden, and immune dysregulation — with protocols designed and supervised by a board-certified physician. Care that complements your existing treatment, never replaces it.
★ Board-Certified Internal Medicine · 25+ years | Physician-owned & operated
— Treatments & Therapies
Our Treatments & Therapies
Ozone Therapy
EBOO Ozone Therapy
Detox & immune support
Explore →
Ozone Sauna
HOCATT™ Ozone Sauna
Whole-body reset
Explore →
Medical Aesthetics
Regenerative Aesthetics
Skin & regenerative
Explore →
— How It Works
A Clear Path to Root-Cause Care
01
Start With a Call
A 1:1 phone consultation with Dr. Volpp. Review your history, ask questions, and get an honest answer on whether we can help.
02
A Protocol for Your Biology
Dr. Volpp reviews your full history and labs, then designs a physician-supervised protocol around your specific root contributors — not a template, never an upsell.
03
Treatment & Measured Follow-Up
EBOO, HOCATT™, and regenerative therapies under direct physician oversight — with objective markers tracked and your plan adjusted as you respond.
— Learn · Medical Ozone Therapy
How Medical Ozone Works in the Body
Medical ozone introduces a brief, controlled oxidative signal. Research suggests this may prompt the body’s own adaptive antioxidant and repair pathways — so the goal is to support your physiology, not override it.
Our education hub walks through the biology, the current evidence, candidacy, and how EBOO and HOCATT™ compare — so you understand the mechanism before the outcome.
Hormesis
A small, controlled ozone stressor may stimulate the body’s own antioxidant pathways, including Nrf2, glutathione, and SOD.
Immune Modulation
Research suggests ozone may influence cytokine signaling and immune response — of interest in chronic infection and immune dysregulation.
Filtration-Based Delivery
With EBOO, blood is circulated through a hollow-fiber filter as part of the treatment circuit; researchers are exploring its role in supporting normal clearance.
Two Delivery Methods
EBOO blood-circuit therapy and the HOCATT™ transdermal sauna — each suited to different needs and conditions.
— Conditions We Support
Where Would You Like to Start?
Select the concern that sounds like you. Each path explains how our physician-led protocols may help.
Chronic Fatigue & Long COVID
Mold & Environmental Toxins
Lyme Disease & Co-Infections
Autoimmune Conditions
Chronic Inflammation
Pre & Post-Op Recovery
Skin Conditions
Athlete Recovery
— Why SynergyO3 Is Different
A physician runs every protocol — and is in the room.
Many “wellness” clinics offer ozone without a doctor present. At SynergyO3, Dr. Volpp — board-certified in Internal Medicine and fellowship-trained in Allergy & Immunology — designs your protocol, calibrates your dosing, and is clinically responsible for every session.
Physician-Led, Not Trend-Led
Every protocol designed & supervised by Dr. Volpp, MD.
Root Cause, Not Symptoms
We address inflammation, oxidative burden, and immune dysregulation.
Integration, Not Opposition
We work alongside your existing care team — never a replacement.
Transparency, Not Mystery
Mechanism explained before outcome. Written pricing before any service.
— Patient Stories
What Our Patients Say
★★★★★
“I received EBOO the other day and feel great. I have been working nights for the past 18 months and felt run down. After treatment, I felt rejuvenated and the inflammation in my joints seems to have eased. Dr. Volpp and her staff were professional and made me feel comfortable from my consultation through treatment. I look forward to seeing results as I continue treatment.”
Nate Wright
1 week ago · Google
★★★★★
“I have been coming here for EBOO a few weeks now. I have truly enjoyed my experience, the staff and doctor are so welcoming and truly make me feel welcome and at home! Thank you SynergyO3 team!”
Kerri Selby
10 months ago · Local Guide
★★★★★
“My husband and I have been to many different EBOO clinics across the country and Dr. Heather and her team are the best! We have seen the most health results out of any clinic due to their UV light add on and their knowledgeable, compassionate care. We went from barely functioning to thriving and having energy for the first time in years. We finally have our life back! Their pricing is very competitive too.”
Jessie
2 months ago · Google
Verified Google reviews. Individual results are not typical and may vary. These statements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease.
— Common Questions
Answers Before You Book
Still have questions? Speak with our team directly — we’re happy to talk through your situation before you commit to anything.
Yes. Every treatment at SynergyO3 is designed and supervised by Dr. Heather Volpp, MD. She reviews your full medical history, calibrates dosing, and is clinically responsible for each session — the key safety difference from non-physician “wellness” clinics.
A phone consultation with Dr. Volpp is $150, credited toward your first EBOO treatment. EBOO is $1,100/session (packages available); HOCATT™ is $160/session. Insurance is not accepted, but HSA/FSA superbills are provided, and you receive written pricing before any service.
Call (760) 450-4602 or book a phone consultation online. Dr. Volpp will review your history and tell you honestly whether our protocols are appropriate for your situation — with no obligation.
Ozone therapy is not FDA-approved for specific conditions and is offered as an integrative medical treatment under physician supervision. These statements have not been evaluated by the FDA. Individual results vary.
It depends on your situation. Many patients begin with a short series and reassess; more complex cases may require more over several months. Dr. Volpp evaluates your response after each session and adjusts the protocol.
No. SynergyO3 works alongside your existing care team as a complementary layer — never as a replacement. Dr. Volpp coordinates with your other providers when clinically appropriate.
— Request a Consultation
Take the first step today.
Leave your details and our team will reach out within one business day to schedule your phone consultation with Dr. Volpp.
Prefer to talk now? Call (760) 450-4602
✓ Reviewed personally by Dr. Volpp, MD
✓ No obligation — a clear, honest assessment
✓ Consultation fee credited toward treatment
— Get Started
Ready to find the root cause?
Your body is built to seek its own balance — it just needs the right support to get there. At SynergyO3, we focus on the root contributors to chronic symptoms with physician-led, integrative care designed around your biology.
— Inside SynergyO3
A Real Clinic. Real Care.
A look inside our physician-led practice in Encinitas — the space, the technology, and the team behind your care.
— Visit Us
1011 Devonshire Dr, Suite C2 · Encinitas, CA
Mon–Fri · 8:00am–5:00pm PT · Physician-owned & operated
