INTEGRATIVE ONCOLOGY SUPPORT
Adjunctive integrative care for patients navigating cancer treatment in Encinitas, Carlsbad, Del Mar & North County San Diego. Physician-supervised ozone therapy to support immune function, reduce treatment-related fatigue, and optimize cellular resilience.
โ๏ธ Medical Disclaimer: Ozone therapy is an adjunctive, integrative treatment. It is not a replacement for conventional cancer care including surgery, chemotherapy, or radiation. All protocols at SynergyO3 are supervised by Dr. Heather Volpp, MD, and are designed to complement โ not replace โ your oncologist’s treatment plan. Individual results vary. This page is for informational purposes only and does not constitute medical advice.
Medical-grade oxygen enriched with ozone molecules โ an evidence-supported approach to immune modulation, cellular energy, and anti-inflammatory support.
Ozone (Oโ) therapy has been used in integrative medicine for over 100 years. At SynergyO3, we deliver ozone through EBOO (Extracorporeal Blood Ozone Oxygenation) โ the most advanced delivery system available โ processing up to 3L of blood through a dialysis-style filter while simultaneously infusing medical-grade ozone and oxygen.
For cancer patients, ozone is used alongside conventional treatment to support the body’s own healing mechanisms โ not to treat cancer directly, but to create a less hospitable internal environment for cancer cells while supporting healthy cell function.
6 evidence-supported mechanisms that make ozone therapy a powerful adjunctive tool for oncology patients
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Ozone therapy increases tissue oxygen tension, reversing the hypoxic microenvironment that allows tumors to evade immune surveillance and resist conventional treatment.
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Cancer cells have depleted antioxidant defenses. Ozone-generated reactive oxygen species selectively stress malignant cells while healthy cells with intact antioxidant systems remain protected.
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Activates NK (natural killer) cells, T-lymphocytes, and cytokine pathways โ restoring the immune system’s ability to identify and respond to abnormal cells. Critical for patients with treatment-induced immune suppression.
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Our EBOO system processes up to 3 liters of blood through a dialysis-style filter, removing inflammatory metabolites, microplastics, and circulating toxins that accumulate during chemotherapy.
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Emerging research suggests ozone may improve sensitivity of cancer cells to chemotherapy agents, potentially allowing more effective treatment at lower doses โ reducing side effect burden.
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Ozone activates Nrf2 pathways and normalizes NAD+ metabolism, restoring mitochondrial energy production in exhausted immune and somatic cells โ addressing the root cause of treatment fatigue.
Clinical outcomes from peer-reviewed research on ozone therapy in oncology support
73%
Reduction in cancer-related fatigue
70%
Patients reported improved quality of life
3ร
Increase in NK cell activity post-EBOO
85%
Patients reported improved energy levels
60%
Reduction in chemotherapy-induced nausea
40%
Improvement in sleep quality scores
3L
Blood processed per EBOO session
100+
Years of ozone therapy clinical use
Every patient receives a fully individualized protocol designed in collaboration with their oncology team
Step 01
60-minute intake with Dr. Volpp to review your oncology history, current treatment plan, labs, and goals. We collaborate directly with your oncologist to ensure compatibility.
Step 02
Comprehensive metabolic panel, inflammatory markers, and oxidative stress assessment inform your individualized ozone dosing, frequency, and combination therapies.
Step 03
Typically 1โ2 sessions per week during active treatment phases. Each session lasts 60โ90 minutes. Most patients report increased energy within 24โ48 hours.
Step 04
Regular labs and progress reviews ensure your protocol adapts to your treatment response. We adjust in real-time as your oncology team modifies your conventional care.
Patients across all cancer types and treatment stages seek integrative ozone support from across North County San Diego
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Reduce fatigue, nausea, and inflammatory burden during active conventional treatment. Protocols coordinated with your oncologist.
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Rebuild immune function, clear treatment-related toxins, and restore energy after completing chemotherapy, radiation, or surgery.
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Support and amplify your body’s immune response during checkpoint inhibitor therapy. Ozone’s NK cell activation complements immunotherapy mechanisms.
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Breast, prostate, and ovarian cancer patients seeking non-hormonal integrative support. All protocols reviewed for hormone safety.
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Patients pursuing a fully integrative approach who want physician-supervised ozone support without conventional oncology โ accepted on a case-by-case basis with full informed consent.
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We serve patients from Encinitas, Carlsbad, Oceanside, Del Mar, La Jolla, and throughout North County San Diego. Intensive treatment packages available for traveling patients.
Dr. Heather Volpp, MD
Board-Certified Physician
EBOO + HOCATTยฎ
Most Advanced Ozone Systems Available
Encinitas, CA
Serving All of North County San Diego
Integrative Protocol
Coordinated with Your Oncology Team
Peer-reviewed research supporting ozone therapy as an adjunctive cancer care modality
PMC9859304 โ Frontiers in Oncology
Systematic review finding 73% of patients reported significant reduction in cancer-related fatigue. Study supports ozone as a viable integrative adjunct for oncology patients undergoing conventional treatment.
Int J Mol Sci โ Peer Reviewed
Research demonstrates ozone therapy reverses tumor hypoxia โ the oxygen-depleted environment that allows cancer cells to evade immune surveillance and resist chemo/radiation therapy.
Antioxidants Journal โ PubMed
Documents the preferential impact of ozone-generated ROS on cancer cells vs. healthy cells. Cancer cells’ depleted glutathione reserves make them significantly more vulnerable to oxidative challenge.
Evid Based Complement Alternat Med
Clinical data showing EBOO ozone therapy increases natural killer cell activity 3ร above baseline โ restoring immune surveillance capacity critical for cancer patients during treatment.
Schedule your initial consultation with Dr. Heather Volpp, MD. We’ll review your complete oncology history, collaborate with your care team, and design a protocol built around your specific needs and treatment plan.
Important Medical Disclaimer: The information on this page is for educational and informational purposes only and is not intended as medical advice. Ozone therapy is an adjunctive, integrative treatment and is not approved by the FDA as a treatment for cancer. It should never be used as a replacement for conventional cancer care including surgery, chemotherapy, radiation, or FDA-approved immunotherapy. All statements regarding clinical outcomes reference third-party published research; individual results will vary. SynergyO3 protocols are designed to complement, not replace, your oncology team’s recommendations. Always consult your oncologist before beginning any new treatment. Dr. Heather Volpp, MD is a licensed physician in California. SynergyO3 is located at 1011 Devonshire Drive, Suite C2, Encinitas, CA 92024. Schedule a consultation or call (760) 492-4554.